Workers exposure to formaldehyde in the tanneries of the Tuscany leather district, following the use of biocides in the manufacturing process

  • Carla Poli UO Prevenzione Igiene e Sicurezza nei Luoghi di Lavoro, Azienda USL Toscana Centro, Regione Toscana
  • Tonina Enza Iaia UO Prevenzione Igiene e Sicurezza nei Luoghi di Lavoro, Azienda USL Toscana Centro, Regione Toscana
  • Stefano Taddei UO Prevenzione Igiene e Sicurezza nei Luoghi di Lavoro, Azienda USL Toscana Centro, Regione Toscana
  • Luciano Arena UO Prevenzione Igiene e Sicurezza nei Luoghi di Lavoro, Azienda USL Toscana Centro, Regione Toscana
  • Lorella Luti UO Prevenzione Igiene e Sicurezza nei Luoghi di Lavoro, Azienda USL Toscana Centro, Regione Toscana
  • Gianluca D’Ermilliis UO Prevenzione Igiene e Sicurezza nei Luoghi di Lavoro, Azienda USL Toscana Centro, Regione Toscana
  • Anna Cenni Laboratorio di Sanità Pubblica, Azienda USL Toscana sud est, Siena, Regione Toscana
  • Maria Cristina Apresa Laboratorio di Sanità Pubblica, Azienda USL Toscana sud est, Siena, Regione Toscana
Keywords: formaldehyde cessors, leather, tannery, worker exposure

Abstract

In 2016, following the European classification as carcinogen (category 1B), formaldehyde was practically eliminated among the products used in the tanning companies of the leather district in Tuscany. A survey, conducted by the competent local Health Authority, revealed the use, in the leather processing cycle, of various products containing biocides, some of which known as formaldehyde cessors. In consideration that no risk assessment document took into account exposure to formaldehyde, in the period 2017-2019 environmental monitoring surveys with personal and static samplings were conducted in five different companies to evaluate the real release of this substance during processing carried out using mixtures containing biocides. Although the picture still needs to be studied in depth, anomalous exposures of workers emerged during the unloading of the hides from the drums in a company that used isothiazolinones for resining treatment, and in a company that used "bronopol" (2-bromo-2-nitropropane-1,3-diol - CAS 52-51-7) during the fattening of the hides. The preliminary data obtained demonstrate that workers' exposure to formaldehyde can be present in relation to the type and quantity of biocides in the mixtures used.

References

ACGIH. American Conference of Governmental Industrial Hygienists: Threshold limit values for chemical substances and biological exposure indices. Cincinnati, Ohio, 2019.

Costantini, A.S., Paci, E., Miligi, L., Buiatti, E., Martelli, C., Lenzi, S., 1989. Cancer mortality among workers in the Tuscan tanning industry. Br. J. Ind. Med. 46(6), 384-388.

Iaia, T.E., Bartoli, D., Calzoni, P., Comba, P., De Santis, M., Dini, F., Farina, G.A, Valiani, M., Pirastu, R., 2006. A cohort Mortality Study of leather tanners in Tuscany, Italy. Am. J. Ind. Med. 49(6), 452-459.

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Volume 62: Wood dust and Formaldehyde. WHO, Lyon, France, 1995.

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Volume 88: Formaldehyde, 2-Butoxyethanol and 1-tert-Butoxypropan-2-ol, WHO, Lyon, France, 2006.

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Volume 100 F: Chemical agents and related occupations, WHO, Lyon, France, 2012.

Nielsen, G.D., Larsen, S.T., Wolkoff, P., 2017. Re-evaluation of the WHO (2010) formaldehyde indoor air quality guideline for cancer risk assessment. Arch. Toxicol. 91(1), 35–61.

Sathish, M., Madhan, B., Raghava, Rao J., 2019. Leather solid waste: An eco-benign raw material for leather chemical preparation - A circular economy example. Waste Manag. 87, 357-367.

Published
2021-04-29