Effects of municipal waste effluent on albino rat [Rattus norvegicus (Amori)]

Matthew Chidozie Ogwu, Temitope Sherifat Oladeji

Abstract


The aim of the present investigation is to determine the effect of heavy metal pollutants such as Lead, Mercury,
Cadmium, Chromium and Arsenic in municipal waste on Albino rat (Rattus norvegicus) by using a set of behavioral,
biochemical and haematological parameters. The municipal waste effluent was collected from the Capitol dumpsite of
the University of Benin, Ugbowo Campus. The pollutants were found to be present in toxic concentrations. The rats
were exposed to 40%, 70%, 100% and Control (0%) effluent concentration. Behavioral changes especially in aggression
and cannibalism, which increased with increasing effluent concentration were observed. The results of biochemical
analysis after 5 weeks indicate that there is reduced glucose, conjugated bilirubin and total cholesterol with increasing
effluent concentration and an increased total glyceride, creatinine and urea with increasing effluent concentration.
The result of the haematological analysis after 5 weeks showed a statistically significant difference in total leucocytes,
neutrophils, lymphocytes, monocytes, eosinophils and basophils. The values for lymphocytes (%) were 39.60±3.55,
38.55±2.76, 35.32±3.01 and 31.33±2.56 for control (%), 40%, 70% and 100% effluent concentration in that order


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